In an era where chemical management is becoming a core business imperative, Canadian retailers and CPG companies are entering uncharted territory as regulations on PFAS and other chemicals of concern rapidly evolve. With most PFAS now classified as toxic under the Canadian Environmental Protection Act (CEPA) and a phased regulatory strategy in motion, businesses face complex compliance challenges spanning different product categories. This panel brings together industry experts to examine how leading companies are responding to proactively identify, substitute, and eliminate PFAS from their supply chains. Drawing on lessons from real-world experiences and market shifts, panellists will share strategies for enhancing supply chain transparency, conducting robust risk assessments, implementing product testing, and leveraging voluntary phase-outs and labelling initiatives.